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Pieter J Wouters Selected Research

Parenteral Nutrition

12/2022Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial.
1/2022C-reactive protein rise in response to macronutrient deficit early in critical illness: sign of inflammation or mediator of infection prevention and recovery.
1/2021Role of age of critically ill children at time of exposure to early or late parenteral nutrition in determining the impact hereof on long-term neurocognitive development: A secondary analysis of the PEPaNIC-RCT.
10/2020Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU.
1/2020Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study.
1/2020Long-term developmental effect of withholding parenteral nutrition in paediatric intensive care units: a 4-year follow-up of the PEPaNIC randomised controlled trial.
1/2020Effect of early parenteral nutrition during paediatric critical illness on DNA methylation as a potential mediator of impaired neurocognitive development: a pre-planned secondary analysis of the PEPaNIC international randomised controlled trial.
11/2019The GH Axis in Relation to Accepting an Early Macronutrient Deficit and Outcome of Critically Ill Patients.
8/2019The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT.
1/2019Long-term developmental effects of withholding parenteral nutrition for 1 week in the paediatric intensive care unit: a 2-year follow-up of the PEPaNIC international, randomised, controlled trial.
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Pieter J Wouters Research Topics

Disease

72Critical Illness (Critically Ill)
12/2022 - 02/2003
13Infections
01/2022 - 05/2012
9Hyperglycemia
02/2015 - 02/2003
7Inflammation (Inflammations)
01/2022 - 02/2003
7Hypoglycemia (Reactive Hypoglycemia)
02/2013 - 02/2003
6Polyneuropathies (Polyneuropathy)
03/2007 - 02/2003
5Sepsis (Septicemia)
12/2018 - 01/2004
4Acute Kidney Injury (Acute Renal Failure)
03/2008 - 02/2003
3Septic Shock (Toxic Shock Syndrome)
12/2018 - 07/2015
2Liver Diseases (Liver Disease)
07/2014 - 07/2009
1Glucocorticoid Receptor Deficiency
06/2022
1Fibrosis (Cirrhosis)
01/2022
1Starvation
01/2020
1Muscle Weakness
11/2019
1Bacterial Infections (Bacterial Infection)
08/2019
1Invasive Fungal Infections
08/2019
1Shock
12/2018
1Adrenal Insufficiency (Adrenal Gland Hypofunction)
07/2015
1Cushing Syndrome
04/2014
1Neoplasms (Cancer)
01/2014
1Muscular Atrophy (Muscle Atrophy)
01/2012
1Cholestasis
07/2009
1Disseminated Intravascular Coagulation
05/2008
1Oliguria
03/2008
1Chronic Kidney Failure (Chronic Renal Failure)
03/2008
1Insulin Resistance
10/2007
1Muscular Diseases (Myopathy)
03/2007

Drug/Important Bio-Agent (IBA)

31Insulin (Novolin)FDA Link
01/2022 - 02/2003
12Blood Glucose (Blood Sugar)IBA
11/2017 - 02/2003
9Glucose (Dextrose)FDA LinkGeneric
01/2022 - 01/2004
7Hydrocortisone (Cortisol)FDA LinkGeneric
01/2020 - 10/2006
5Proteins (Proteins, Gene)FDA Link
01/2022 - 04/2011
5Adrenocorticotropic Hormone (ACTH)FDA Link
01/2020 - 04/2013
5Thyroid HormonesIBA
03/2013 - 07/2003
3CytokinesIBA
01/2022 - 10/2003
3Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020 - 01/2012
3LipidsIBA
11/2017 - 01/2004
3Iodide Peroxidase (Deiodinase)IBA
12/2005 - 07/2003
2GlucocorticoidsIBA
06/2022 - 10/2018
2C-Reactive ProteinIBA
01/2022 - 02/2015
2Hormones (Hormone)IBA
01/2022 - 11/2017
2hydroxide ionIBA
03/2020 - 10/2003
2Carrier Proteins (Binding Protein)IBA
01/2020 - 10/2018
2Insulin-Like Growth Factor I (IGF-1)IBA
11/2019 - 07/2004
2Insulin-Like Growth Factor Binding ProteinsIBA
11/2019 - 07/2004
2Amino AcidsFDA Link
11/2017 - 05/2014
2Mannose-Binding Lectin (Mannan-Binding Lectin)IBA
01/2016 - 01/2014
2LectinsIBA
01/2016 - 01/2014
2Peptide Hydrolases (Proteases)FDA Link
02/2015 - 01/2012
2Hypoglycemic Agents (Hypoglycemics)IBA
02/2013 - 03/2011
1Cortisone ReductaseIBA
06/2022
1Protein Isoforms (Isoforms)IBA
06/2022
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
06/2022
1PlasticizersIBA
01/2022
1CalciumIBA
01/2022
1Biological ProductsIBA
01/2022
1Diethylhexyl Phthalate (DEHP)IBA
01/2022
1PlasticsIBA
01/2022
11,25-dihydroxyvitamin DIBA
03/2020
125-hydroxyvitamin DIBA
03/2020
1Vitamin D-Binding ProteinIBA
03/2020
1Indicators and Reagents (Reagents)IBA
01/2020
1Mannose ReceptorIBA
08/2019
1Glucagon (Glukagon)FDA Link
11/2017
1Serine Proteases (Serine Protease)IBA
01/2016
1SteroidsIBA
07/2015
1HMGB1 Protein (HMG1)IBA
02/2015
1LigandsIBA
02/2015
1Receptor for Advanced Glycation End ProductsIBA
02/2015
1S100A12 ProteinIBA
02/2015
1BilirubinIBA
07/2014
1Mannose-Binding Protein-Associated Serine Proteases (Mannose-Binding Protein-Associated Serine Protease)IBA
01/2014
1FicolinsIBA
01/2014
1EnzymesIBA
04/2013
1Scavenger Receptors (Scavenger Receptor)IBA
04/2013
1Messenger RNA (mRNA)IBA
01/2012
1Myosins (Myosin)IBA
01/2012
1Protein AggregatesIBA
04/2011
1Biomarkers (Surrogate Marker)IBA
10/2010
1Phosphopyruvate Hydratase (Enolase)IBA
10/2010
1Dacarbazine (DIC)FDA LinkGeneric
05/2008
1CreatinineIBA
03/2008
1AdiponectinIBA
10/2007
1cortisol binding globulinIBA
10/2006
1AlbuminsIBA
10/2006
1thyroxine sulfateIBA
12/2005
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
08/2005
1Triiodothyronine (Liothyronine)FDA LinkGeneric
08/2005
1Reverse TriiodothyronineIBA
08/2005
1NF-kappa B (NF-kB)IBA
08/2005

Therapy/Procedure

22Parenteral Nutrition
12/2022 - 08/2011
21Therapeutics
05/2014 - 02/2003
15Critical Care (Surgical Intensive Care)
01/2022 - 10/2003
12Glycemic Control
02/2015 - 02/2003
7Enteral Nutrition (Feeding, Tube)
11/2019 - 08/2011
2Artificial Respiration (Mechanical Ventilation)
01/2017 - 03/2007
1Muscle Denervation
01/2022
1Length of Stay
05/2012
1Denervation
01/2012
1Renal Replacement Therapy (Therapies, Renal Replacement)
03/2008